Coumarin-1,2,3-triazole hybrids as leading-edge anticancer agents

Cancer is one of the most feared and dreaded diseases across world. In clinical practice, a variety anticancer agents natural, semi-synthetic synthetic origin exist, but they suffer from side effects drug resistance, so are insufficient to combat disease. Coumarins bicyclic benzene-pyrone-fused phytomolecules with wide range biological effects, including powerful activity on numerous cell lines. Additionally, serve as an adaptable scaffold research hub for medicinal chemists. On other hand, triazoles nitrogen-containing heterocycles having remarkable pharmacological activities. Due better compatibility human metabolic system, synthesis nature inspired hybrid compounds fewer at forefront current research. last decade, huge has been published coumarin-1,2,3-triazole hybrids showing potent activities various types cancer. This review offers recent, thorough literature compilation contemporary development based coumarin-1,2,3-triazoles potential leads throughout previous 10 years.